In the Patel Lab, we are seeking to develop innovative strategies to diagnose, characterize, and monitor cancer with the ultimate goal of improving patient outcomes. Our research aims to understand and exploit new classes of DNA and RNA biomarkers that are shed from tumor cells into a patient’s bloodstream. We are developing ultrasensitive diagnostic tools to enable measurement of trace amounts of these circulating DNA and RNA fragments that harbor cancer-specific genomic signatures. In parallel, we are investigating clinical applications to take advantage of the exceptional specificity of these biomarkers.
Our research draws upon expertise from diverse fields such as clinical oncology, molecular biology, chemistry, computer science, and microfluidics. We rely on extensive collaborations with both scientists and clinicians, and we are always open to new collaborations from investigators with good ideas.